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In contrast, BACH1 exerts its pro-ferroptotic role by modulating the expression of genes (e.g., FTH1) involved in key regulatory pathways of ferroptosis in cancer cells [87, 88]

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Blood 105 , 22942299 (2005)

121 The concept of cognitive reserve also becomes particularly relevant during midlife, when its longterm implications are more apparent

Improvements in clinical trials methodologies, the introduction of no fewer than nine biologic agents with distinct mechanisms of action, and the development of better strategies for the use of such agents have all contributed to the new age in RA therapeutics